Selected skin literature

DSM Colorimeter

The impact of incisional negative pressure wound therapy (iNPWT) on scar quality and patient-reported outcomes: A within-patient-controlled, randomised trial

Wound Repair and Regeneration. 2022; 30(2). DOI: 10.1111/wrr.13001

Aim of study: To establish if iNPWT results in improved scar outcomes in comparison to standard care. Objective scar coloration evaluation was performed with the DSM-II.

Conclusion: The DSM-II demonstrated consistent measurements of scar erythema and melanin, showing no significant differences between scar and unaffected skin values. This suggests that iNPWT is of little benefit as a scar-improving therapy.

DermaScan

Comparison between high-frequency ultrasonography (DermaScan C Ver. 3) and Histopathology in atopic dermatitis.

Skin Research and Technology. 2013; 19(4). DOI: 10.1111/srt.12064

Aim of study: To compare ultrasound images to histological images among patients suffering from atopic dermatitis. Ultrasound images were obtained using the DermaScan to assess skin echogenicity and thickness of the hypoechoic band.

Conclusion: There is a strong agreement between ultrasonography and histological features in evaluation of atopic dermatitis. All pathological changes of atopic dermatitis influenced the ultrasound image, indicating a high accuracy.

DermaScan

​High resolution topographical maping of warm and cold sensitivities

Clinical Neurophysiology. 2008; 119(11); DOI: 10.1016/j.clinph.2008.08.018

Aim of study: To explore the thermal sensitivity distribution over the glabrous skin of the hand in males and females. DermaScan ultrasound imaging was used to investigate the effect of epidermis thickness on thermal sensitivity.

Conclusion: Thermal sensitivity of the hand is highly heterogenous. The DermaScan enabled the study to conclude that there was no correlation between warm/cold thresholds and epidermal thickness.

DermaScan

A prospective multicentre clinical trial evaluating the efficacy and safety of a hyaluronic acid-based filler with Tri-Hyal technology in the treatment of lips and the perioral area

Journal of Cosmetic Dermatology. 2022; 22(2). DOI: 10.1111/jocd.15169

Aim of study: To evaluate efficacy, longevity, and safety of a cross-linked hyaluronic acid-based filler with Tri-Hyal technology in the treatment of lips, nasolabial folds, and marionette lines. The DermaScan high-frequency ultrasound imaging was used to assess dermal density.

Conclusion: The filler demonstrated high efficacy and safety in all indications. The DermaScan ultrasound imaging showed significant increases in collagen density following filler treatment for nasolabial folds.

DermaScan

Intradermal Treatment with a Hyaluronic Acid Complex Supplemented with Amino Acids and Antioxidant Vitamins Improves Cutaneous Hydration and Viscoelasticity in Healthy Subjects

Antioxidants. 2024; 13(7). DOI: 10.3390/antiox13070770

Aim of study: To study the response of a facial injection on skin rejuvenation. The DermaScan high-frequency ultrasound imaging was used to assess dermal density.

Conclusions: The facial treatment promotes a rejuvenated appearance of the skin. The DermaScan ultrasound imaging found a significant increase in in skin density, indicating increased collagen content.

DermaLab - Elasticity, hydration, color & ultrasound

Quantitative Assessment of New Frontiers in Dermatochalasis and Periorbital Hyperpigmentation Treatment: The Role of Cross-Linked Porcine Collagen

Aesthetic Plastic Surgery. 2024; 49. DOI: 10.1007/s00266-024-04407-1

Aim of study: To evaluate the effectiveness, clinical safety, and patient satisfaction associated with the utilization of collagen dermal fillers in individuals with dermatochalasis and periorbital hyperpigmentation. Multiple DermaLab probes were used to analyse skin parameters.

Conclusion: The DermaLab colori probe detected a significant increase in skin lightness, while the hydration probe showed a significant improvement in skin moisture levels. Injections with cross-linked porcine collagen dermal filler may offer a minimally invasive solution for improving skin laxity and reducing discoloration.

DermaLab - Color

A randomized investigation of film-forming silicone gel in superficial partial thickness face and neck burn patients: Indication of improved early scar pigmentation outcomes

Journal of the International Society for Burn Injuries. 2024; 50(6). DOI: 10.1016/j.burns.2024.03.024

Aim of study: To explore the effect of topical silicone compared to routine treatment of conservatively managed burns to the face and neck. Scar pigmentation was measured using the DermaLab colori probe.

Conclusion: Silicone gel treatment was associated with a reduction in DermaLab pigmentation scores, indicating improved wound healing. A significant improvement in scar pigmentation was observed in silicone-treated wounds six weeks after burn injury.

DermaLab - TEWL, hydration & elasticity

Efficacy, Safety, and Tolerance of a New Injection Technique for High- and Low-Molecular-Weight Hyaluronic Acid Hybrid Complexes

ePlasty. 2015; 15. PMID: 26491508

Aim of study: To investigate the efficacy, security, and tolerability of a new medical device for facial skin rejuvenation. The DermaLab TEWL-, hydration-, and elasticity probes were used to evaluate product results.

Conclusion: Measurements with the DermaLab probes showed significant improvements in facial hydration, elasticity and TEWL values. The treatment represents a good and safe treatment option to restore vitality and turgidity of skin.

DermaLab - TEWL, hydration & elasticity

Improved barrier function observed in cultured skin substitutes developed under anchored conditions

Skin Research and Technology. 2008; 14(4). DOI: 10.1111/j.1600-0846.2008.00225.x

Aim of study: To evaluate a new method of producing skin substitutes for in vitro product testing/toxicity-testing purposes. The DermaLab TEWL probe was used to measure water loss in vitro.

Conclusion: The DermaLab TEWL measurements showed a significantly lower TEWL in the skin substitute, indicating a less permeable barrier. The new method of producing skin substitutes has good potential as an in vitro permeability and toxicity model.

DermaLab - pH & hydration

The Disturbed Microbial Niches of Itchy Scalp

Journal of Cosmetic Dermatology. 2025; 24(1). DOI: 10.1111/jocd.70010

Aim of study: To investigate the relationship between scalp itching and microorganisms. DermaLab pH and hydration probes were used to assess scalp skin parameters.

Conclusion: The DermaLab hydration probe revealed significantly higher stratum corneum hydration in the scalp, suggesting a higher degree of hydration might be related to scalp itch. No relationship was found between pH and scalp itch. The findings point to scalp cleansing and microbial regulation as potential strategies against itch

DermaLab - Sebum

Clinical Study on the Application of Non-Thermal Biocompatible Plasma for Acne-Prone Skin Treatment

Applied Science and Convergence Technology. 2024; 33(4). DOI: 10.5757/ASCT.2024.33.4.83

Aim of study: To evaluate the efficacy of a plasma device for the treatment of acne-prone skin. The DermaLab sebum module was used to evaluate the suitability of the test product for the targeted skin type.

Conclusion: The DermaLab sebum module demonstrated a significant decrease in skin sebum among the treatment group. The new treatment is thus suitable for acne-prone skin.